1. Twisties - You will be initially concerned about the MS's ability due to it's height (and looks) though you will quickly be grinning in the twisties. The bike is true to test reports that it is a blast in any turns. Ground clearance is an issue for some "advanced” riders, it is not for most.
2. Comfort/Wind - The ergonomics are very comfortable, very upright, it took a while for me to get use to my feet being so underneath me, though I feel very comfortable now. My guess is that the wind will be your biggest concern. For a minimal fairing it does a decent job though it is no VFR. The new 2005 MS screen or the comfort screen with lip appears to improve wind protection somewhat, your legs fit in the tank recess for decent protection (again do not compare this to a VFR, FJR, etc...) Since your not a 6'4" rider, the MS may be very good for you with, especially with a different windscreen than the 2004 (then it would probably hit you perfectly in the top of the helmet.
2b. Seat - You should probable plan on spending some cash on a corbin or sargent seat (some love the DP comfort seat by Ducati) as the stock seats have not be great for most on 100 plus miles including myself. I will be getting the sargent for Christmas, the Corbin may be more comfortable though I am compromising for the looks of the sargent (both websites have photos as well as in this sites photo section). 250 should be good with a seat upgrade.
3. See 2a
4. Sweepers - I love them on this bike (even though my Ninja days are long gone).
5. Brakes - The 2004 brakes are very very good for the price of this bike, with two 320mm semi-floating discs, four-piston calipers in the front. Some have experienced some brake shudder, it is not be a problem for me.
6. Engine - It is the best used (84hp or 92hp depending on were you measure) that I have experienced. I did not think I would be buying this bike because of the engine power until I rode it, it feels strong with excellent torque with a smooth gearbox. You will probably love it compared the 900SS engine. I am not wishing for anymore power, it has strong acceleration (not like a Japanese liter superbike of course), with the power right there all the time (many including myself switched to the 14 tooth sprocket and I really like the results), and it does not throttle wheelies in 1st and 2nd gear if you care about that.
7. Reliability - Appears good so far, the jury is still out, I have had zero problems at this time (only 10 months).
If I give this bike up in the next 4 years, it will not be because I want to replace it, it would be for other reasons and none of them good.
Not mentioned about the MS, it is fairly lightweight and feels very light (441), even though it is tall (33.5) it is narrow which makes the height not as much of a factor, the suspension and travel are superior with 43mm inverted Showa, fully adjustable, 6.5 in. travel up front and adjustable Showa monoshock; hydraulic remote pre-load control, 5.6 in. travel in the rear. A great commuter that is a sweet canyon bike and decent sport touring capabilities.
The other riders on this site are equipped with phenomenal knowledge and expereince and will be able to give a much more indepth explanation (This site and it’s members are another bonus for owning an MS, they have helped me out many times

).